To be honest I never made good experiences with universal remote controls. This one does look promising. Any of RGS readers made experience with this one?

Harmony sets the standard for universal remotes with a database of IR codes for 175,000+ devices and easy setup via USB and your computer. Answer a few questions about your [...]

You will never habe trouble to find this remote cotrol – it’s huge. It scares me, it kind of screams at me "Use me, or else!".
Product Info:
With giant buttons, this extra-large remote is easy to use and impossible to lose. Overcome vision or dexterity challenges with this supersized universal remote. Large rubberized buttons simplify use. [...]